• "Halo," Beyonce
• "I Gotta Feeling," The Black Eyed Peas
• "Use Somebody," Kings of Leon - WINNER
• "Poker Face," Lady Gaga
• "You Belong With Me," Taylor Swift

ALBUM OF THE YEAR

• "I Am…Sasha Fierce," Beyonce
• "The E.N.D.," The Black Eyed Peas
• "The Fame," Lady Gaga
• "Big Whiskey and the Groogrux King," Dave Matthews Band
• "Fearless," Taylor Swift

SONG OF THE YEAR

• "Poker Face," Lady Gaga & RedOne
• "Pretty Wings," Hod David & Musze
• "Single Ladies (Put a Ring On It)," Thaddis Harrell, Beyonce Knowles, Terius Nash & Christopher Stewart -WINNER
• "Use Somebody," Caleb Followill, Jared Followill, Matthew Followill & Nathan Followill (Kings of Leon)
• "You Belong With Me," Liz Rose & Taylor Swift

BEST NEW ARTIST

• Zac Brown Band - WINNER
• Keri Hilson
• MGMT
• Silversun Pickups
• The Ting Tings

BEST FEMALE POP VOCAL PERFORMANCE

• "Hometown Glory," Adele
• "Halo," Beyonce
• "Hot N Cold," Katy Perry
• "Sober," Pink
• "You Belong With Me," Taylor Swift

BEST ROCK ALBUM

• "Black Ice," AC/DC
• "Live From Madison Square Garden," Eric Clapton & Steve Winwood
• "21st Century Breakdown," Green Day - WINNER
• "Big Whiskey And the Groogrux King," Dave Matthews Band
• "No Line On The Horizon," U2

BEST RAP/SUNG COLLABORATION

• "Ego," Beyonce & Kanye West
• "Know You Down," Keri Hilson, Kanye West & Ne-Yo
• "Run This Town," Jay-Z, Rihanna & Kanye West
• "I'm On A Boat," The Lonely Island & T-Pain
• "Dead And Gone," T.I. & Justin Timberlake

BEST COUNTRY ALBUM

• "The Foundation," Zac Brown Band
• "Twang," George Strait
• "Fearless," Taylor Swift - WINNER
• "Defying Gravity," Keith Urban
• "Call Me Crazy," Lee Ann Womack

BEST COMEDY ALBUM

• Back From The Dead, Spinal Tap
• A Colbert Christmas The Greatest Gift Of All, Stephen Colbert - WINNER
• Internet Leaks, Weird Al Yankovic
• My Weakness Is Strong, Patton Oswalt
• Suckin’ It For The Holidays, Kathy Griffin
• Tall, Dark & Chicano, George Lopez

BEST MALE POP VOCAL PERFORMANCE

• "This Time," John Legend
• "Love You," Maxwell
• "Make It Mine," Jason Mraz - WINNER
• "If You Don't Know Me by Now," Seal
• "All About the Love Again," Stevie Wonder

BEST POP PERFORMANCE BY A DUO OR GROUP WITH VOCALS

• "I Gotta Feeling," The Black Eyed Peas - WINNER
• "We Weren't Born to Follow," Bon Jovi
• "Never Say Never," The Fray
• "Sara Smile," Daryl Hall & John Oates
• "Kids," MGMT

BEST POP COLLABORATION WITH VOCALS

• "Sea of Heartbreak," Rosanne Cash & Bruce Springsteen
• "Love Sex Magic," Ciara & Justin Timberlake
• "Lucky," Jason Mraz & Colbie Caillat - WINNER
• "Baby, It's Cold Outside," Willie Nelson & Norah Jones
• "Breathe," Taylor Swift & Colbie Caillat

BEST POP INSTRUMENTAL PERFORMANCE

• "Besame Mucho," Herb Alpert
• "Throw Down Your Heart," Bela Fleck - WINNER
• "The Fire," Imogen Heap
• "Phoenix Rise," Maxwell
• "Funk Joint," Marcus Miller

BEST POP INSTRUMENTAL ALBUM

• "In Boston," Chris Botti
• "Legacy," Hiroshima
• "Potato Hole," Booker T. Jones - WINNER
• "Modern Art," The Rippingtons Featuring Russ Freeman
• "Down The Wire," Spyro Gyra